Tim Powers writes a fairly unique style of fantasy, wherein historical events and figures are braided with supernatural elements, usually based on a semi-obscure mythology. When it works well (e.g., Last Call, Declare), it's genius. But it's a kind of genius that you'll either love or hate.

In The Stress of Her Regard, which was Powers' seventh novel (just recently reprinted), the historical figures are Byron, Shelley, and Keats, and the mythology includes vampires and lamia. The plot follows the misadventures of Michael Crawford, an English doctor, as he reacts to the brutal murder of his wife on their wedding night.

I quite enjoyed this, though I thought it was needlessly complicated at times. Possibly the complexity arose from trying to match up the novel's timeline with documented events in the poets' lives (Powers's details are remarkably true to at least the wikipedia versions of the poets' movements around Europe). If you are new to Powers, this might not be the best place to start (try Declare), but it is one of his better novels.